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Keytones-how do they work in your body?

SlimOne
Patient One MediNutritionals
180 gel capsules $58.20

Description
Clinically proven natural ingredients for healthy weight management
* Optimizes breakdown and metabolism of fats
* Maintains youthful hormones linked to peak metabolism
* Promotes desirable and healthy body composition
* Supports lipolysis in conjunction with diet and exercise

Unique Properties
Patient One SlimOne™ unites today’s most dynamic natural ingredients in a breakthrough medinutritional supplement for healthy weight management. With CLA, 7-Keto®, Razberi-K®, and green coffee bean extract, SlimOne supplies advanced nutritional support for desirable body composition, peak metabolic performance, blood sugar support, fat metabolism and more. When used in conjunction with healthy diet and exercise program, Patient One SlimOne helps to maximize weight management results. SlimOne has been carefully formulated to include only gentle, stimulant-free and effective nutrients.

Key Ingredients

CLA:
An omega-6 fatty acid found in grass-fed beef and vegetable oils, CLA (conjugated linoleic acid) is among the most extensively studied weight management nutrients. While its exact mechanisms of action have not been pinpointed, CLA is believed to inhibit the “hunger hormone” leptin, promote lipolysis in white adipose tissue, influence insulin sensitivity, reduce fasting blood glucose and optimize resting metabolic rate. CLA is most commonly associated with lean body mass and healthy body composition.

7-Keto® DHEA
Produced by the adrenal glands, Dehydroepiandrosterone (DHEA) hormone starts to decline around age 30, and has been implicated in metabolic slow-down and age-related weight gain. Restoring DHEA through supplementation is believed to promote a youthful hormonal state that is associated with optimal metabolic rate. 7-Keto DHEA is derived from a plant source that has been purified to match the substance naturally produced in the body. Studies suggest that 7-Keto improves the body’s calorie burning ability at the most basic level by increasing resting metabolic rate—the number of calories burned through regular bodily functions such as breathing. 7-Keto is the weight management metabolite of DHEA–a gentler and safer form that supplies nutritional benefits without influencing testosterone or estrogen levels.

Razberi-K® raspberry ketones
Organic phenolic compounds found in raspberries, ketones are believed to optimize breakdown of fat in the body while promoting peak metabolic function. Some early animal research appears to suggest that raspberry ketones may influence the way lipids are metabolized in fat cells; specifically, raspberry ketones are believed to optimize the breakdown of white adipose tissue. Raspberry ketones have also been found to stimulate the secretion of adiponectin, a hormone that regulates fat storage. Research shows a link between higher levels of adiponectin and lower levels of stored fat.

Green Coffee Bean Extract
Unroasted coffee beans retain their green hue and supply bioactive compounds called chlorogenic acids (CGAs) that are usually destroyed in the coffee bean roasting process. The CGAs found in green coffee beans are believed to promote healthy weight management by influencing sugar metabolism. Research has suggested that CGAs may inhibit the hepatic glucose-6-phosphatase enzyme, thereby modulating glucose production and promoting the blood sugar stability that is associated with healthy weight. SlimOne’s green coffee bean extract is standardized to 50% minimum CGAs.
Research
In one study, 20 men and women took either a CLA supplement (0.6mg) or placebo daily while exercising in standardized 90-minute routines three times weekly. After 12 weeks, researchers reported that body fat was found to be significantly reduced in the CLA group, but not in the placebo group.
In one double-blind, placebo-controlled study designed to evaluate long-term effects of CLA supplementation, 180 volunteers took CLA-free fatty acid (FFA), CLA- triacylglycerol, or placebo over the course of one year. At the study’s end, researchers concluded that supplementation with either the FFA or triacylglycerol form of CLA was associated with significant reductions in body fat mass (BFM) and a tendency towards greater lean body mass.

An early study has suggested that 7-Keto may help with resting metabolic rate of overweight adults. In the study, which included 40 subjects, supplementation with 7-Keto was found to significantly increase resting metabolic rate above basal levels in only seven days. Researchers suggested 7-Keto may benefit overweight individuals with low energy expenditure.

Servings Per Container: 45
Take 4 to 6 capsules daily in divided doses, preferably with a meal, as a dietary supplement or as directed by a qualified health care professional.
Serving Size: 4 Capsules
Amount Per Serving
Calories … 26
Calories from Fat … 25
Total Fat … 2.70g
Saturated Fat … 0.10g
Monounsaturated Fat … 0.30g
Polyunsaturated Fat … 2.30g
Weight Management Proprietary Blend … 3000mg
Conjugated Linoleic Acid 80% oil (CLA); Green Coffee Bean extract (Coffea sp.) (fruit) [Standardized to 50% minimum Chlorogenic acids]; Razberi-K® Raspberry Ketones [4-(4-hydroxyphenyl) butan-2-one]; 7-Keto® DHEA (3-Acetyl-7-oxo-dehydroepiandrosterone)
Other Ingredients: gelatin (capsule), chlorophyll, d-alpha tocopheryl acetate.
This product contains NO egg, fish, peanuts, crustacean shellfish (lobster, crab, or shrimp), soybeans, tree nuts, wheat, yeast, gluten, rice, sugar, or artificial sweeteners, flavors, colors or preservatives.
Razberi-K® is a registered trademark of Integrity Nutraceuticals International, Inc.
7-Keto® is a trademark of InterHealth Nutraceuticals, U.S. Patents No. 5, 585, 371; 6, 153, 606; 6, 489, 313; 7, 553, 829; 7, 199, 116.

References
1. Thom, E, Wadstein J, Gudmundsen O. Conjugated Linoleic Acid Reduces Body Fat in Healthy Exercising Humans. The Journal of International Medical Research. 2001;29:392-396.
2. Kamphuis MMJW, et al. The effect of conjugated linoleic supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects. International Journal of Obesity (2003) 27, 840-847.]
3. Gaullier JM, et al. Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am J Clin Nutr 2004;79:1118 –25.
4. Park KS. Raspberry ketone increases both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes. Planta Med. 2010 Oct;76(15):1654-8. doi: 10.1055/s-0030-1249860. Epub 2010 Apr 27.
5. Ong KW, Hsu A, Tan BKH (2012) Chlorogenic Acid Stimulates Glucose Transport in Skeletal Muscle via AMPK Activation: A Contributor to the Beneficial Effects of Coffee on Diabetes. PLoS ONE 7(3): e32718. doi:10.1371/journal.pone.0032718
6. Morimoto C, et al. Anti-obese action of raspberry ketone. Life Sci. 2005 May 27;77(2):194-204. Epub 2005 Feb 25.
7. Henry-Vitrac C, et al. Contribution of chlorogenic acids to the inhibition of human hepatic glucose-6-phosphatase activity in vitro by Svetol, a standardized decaffeinated green coffee extract. J Agric Food Chem. 2010 Apr 14;58(7):4141-4.
8. Zenk JL, et al. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem. 2007 Sep;18(9):629-34.

Do not use if you are pregnant or nursing. Not for use by individuals under the age of 18 years.

How to Reduce Anxiety – Herbs for Anxiety Reduction – Reduce Anxiety with Herbs

Herbs for Anxiety

Not looking to use Conventional Drugs to help ease Anxiety?  Try some of these herbs.

Licorice Root contains a natural hormone alternative to cortisone, which can help the body handle stressful situations, and can help to normalize blood sugar levels as well as your adrenal glands, providing you with the energy necessary to deal with the stressful situation at hand. Some claim licorice stimulates cranial and cerebrospinal fluid, thereby calming the mind.As a soothing tonic, drink it warm as in a tea.

Kava Kava, an herb from the South Pacific, is a powerful muscle relaxer and analgesic. Kava Kava is also effective at treating depression and anxiety associated with menopause. http://www.care2.com/greenliving/5-herbs-that-reduce-stress-and-anxiety.html#ixzz3zjWfhIxL

Valerian

Some herbal supplements reduce anxiety without making you sleepy (such as L-theanine), while others are sedatives. Valerian (Valeriana officinalis) is squarely in the second category. It is a sleep aid, for insomnia. It contains sedative compounds; the German government has approved it as a treatment for sleep problems.

Valerian smells kind of nasty, so most people take it as a capsule or tincture, rather than a tea. If you want to try it, take it in the evening—not before you go to work! Valerian is often combined with other sedative herbs such as hops, chamomile, and lemon balm.

Hops

Yes, it’s in beer, but you won’t get the tranquilizing benefits of the bitter herb hops (Humulus lupulus)from a brew. The sedative compound in hops is a volatile oil, so you get it in extracts and tinctures—and as aromatherapy in hops pillows.

“It’s very bitter, so you don’t see it in tea much, unless combined with chamomile or mint,” says Blumenthal. Hops is often used as a sedative, to promote sleep, often with another herb, valerian. Note: Don’t take sedative herbs if you are taking a prescription tranquilizer or sedative, and let your doctor know any supplements you are taking.

Chamomile

If you have a jittery moment, a cuppa chamomile tea might help calm you down. Some compounds in chamomile (Matricaria recutita) bind to the same brain receptors as drugs like Valium.

You can also take it as a supplement, typically standardized to contain 1.2% apigenin (an active ingredient), along with dried chamomile flowers. In one study at the University of Pennsylvania Medical Center, in Philadelphia, patients with generalized anxiety disorder (GAD) who took chamomile supplements for eight weeks had a significant decrease in anxiety symptoms compared to patients taking placebo.

http://www.health.com/health/gallery/0,,20669377_2,00.html
Passion Flower

The University of Maryland Medical Center states that passionflower has shown in a few studies to work as well as some of the benzodiazepine medications that are usually prescribed for treating anxiety.

A four-week double-blind study, for example, compared passionflower with oxazepam. Results showed oxazepam worked more quickly, but by the end of the study period, both treatments were shown to be equally effective. Bonus—side effects like daytime drowsiness were fewer with passionflower.

A second study also showed that passionflower helped ease symptoms like anxiety, irritability, agitation, and depression in participants going through withdrawal from an opiate drug addiction.

Dosage: Try one cup of passionflower tea three times daily, 45 drops of liquid extract daily, or about 90 mg/day.

Lavendar

A 2010 multi-center, a double-blind randomized study of lavender oil compared to anti-anxiety medication lorazepam found that both were effective against generalized and persistent anxiety. Bonus — lavender had no sedative side effects.

“Since lavender oil showed no sedative effects,” researchers stated, it could be an effective and “well-tolerated alternative to benzodiazepines” to treat generalized anxiety. An earlier 2000 study found similar results.

Dosage: Try about 80 mg/day of the supplement, or use the oil as an aromatherapy solution.

Lemon Balm

Though usually found in combination with other herbs, lemon balm also has anti-anxiety powers on its own.

Research published in 2004, for instance, gave participants a single dose of lemon balm extract (300 mg or 600 mg) or a placebo, then measured their mood after one hour. The higher dose resulted in reduced stress and improved calmness and alertness. Even the lower dose helped participants do math problems more quickly.

Dosage: Use in aromatherapy, try 300-500 mg of dried lemon balm three times daily, 60 drops daily, or 1/4 to 1 teaspoon of dried lemon balm herb in hot water for a tea four times daily.

Ashwagandha

A 2012 double-blind, placebo-controlled study gave participants either placebo or a capsule containing 300 mg of high-concentration full-spectrum ashwagandha extract, twice a day. The study lasted for 60 days. Those taking the ashwagandha showed significant improvements. Even the levels of the stress hormone cortisol were substantially reduced in those taking the extract. And there were no serious side effects.

In an earlier 2000 study, ashwagandha had anxiety-relieving effects similar to those of lorazepam.

Dosage: Typical dosage is 300 mg standardized to at least one to five percent withanolides, once or twice a day.

L-Theanine

This one isn’t really a herb — it’s a water-soluble amino acid,  but it’s gotten such good research behind it, we had to include it here. It’s found mainly in green tea and black tea and is also available as a supplement.

Studies have found that it acts directly on the brain, helping to reduce stress and anxiety—without causing drowsiness.

Research from 2008, for example, found that those participants taking 50 mg of L-theanine a day had a greater increase in alpha (relaxed brain waves) activity than those who took a placebo.

An earlier 1998 study found that 200 mg a day leads to increased alpha brain waves and a relaxed, yet alert, a state of mind.

A later 2011 study found that it was also associated with reduced anxiety, and was well tolerated and safe for participants.

Dosage: A typical cup of black tea contains only about 25 mg of l-theanine and green tea only about 8 mg. While a cup of tea may be calming, if you want more potent effects, try a supplement, about 200 mg a day.